Open AccessHigh-level expression of cyp51B in azole-resistant clinical Aspergillus fumigatus isolates
Author(s) -
Ahmed Buied,
Caroline B. Moore,
David W. Denning,
Paul Bowyer
Publication year - 2012
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dks451
Subject(s) - aspergillus fumigatus , azole , itraconazole , microbiology and biotechnology , biology , gene , drug resistance , antifungal , genetics
Resistance to azole antifungal drugs in Aspergillus fumigatus that is not mediated by target gene mutations is now common in some locations. The aim of this study was to investigate possible new mechanisms of resistance in non-target resistance.
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