Combination therapy for gonorrhoea: in vitro synergy testing
Author(s) -
Rui P. A. Pereira,
Michelle Cole,
C A Ison
Publication year - 2012
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dks449
Subject(s) - cefixime , azithromycin , gentamicin , antimicrobial , ceftriaxone , neisseria gonorrhoeae , agar dilution , medicine , minimum inhibitory concentration , microbiology and biotechnology , antibiotics , pharmacology , biology
Antimicrobial resistance in Neisseria gonorrhoeae is an increasing problem worldwide and combinations of antimicrobial agents have been recommended to delay the onset of treatment failures. The objective of this study was to obtain in vitro data on the activity of current (ceftriaxone or cefixime plus azithromycin) and alternative (gentamicin plus azithromycin) regimens.
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