High frequency of fluoroquinolone- and macrolide-resistant streptococci among clinically isolated group B streptococci with reduced penicillin susceptibility | Zendy

Kouji Kimura | Zendy; Noriyuki Nagano | Zendy; Yukiko Nagano | Zendy; Satowa Suzuki | Zendy; Junichi Wachino | Zendy; Keigo Shibayama | Zendy; Yoshichika Arakawa | Zendy

Open Access

High frequency of fluoroquinolone- and macrolide-resistant streptococci among clinically isolated group B streptococci with reduced penicillin susceptibility

Author(s) -

Kouji Kimura,

Noriyuki Nagano,

Yukiko Nagano,

Satowa Suzuki,

Junichi Wachino,

Keigo Shibayama,

Yoshichika Arakawa

Publication year - 2012

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dks423

Subject(s) - penicillin , microbiology and biotechnology , streptococcus agalactiae , erythromycin , biology , antibiotics , macrolide antibiotics , streptococcus , group b , agar dilution , medicine , minimum inhibitory concentration , bacteria , genetics

Recently several clinical isolates of Streptococcus agalactiae [also known as group B Streptococcus (GBS)] that have acquired reduced penicillin susceptibility (PRGBS) by amino acid substitutions in the penicillin-binding protein 2X have emerged. The frequency of fluoroquinolone (FQ)- and macrolide-resistant streptococci among PRGBS is not yet known.

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