Outcomes of clofazimine for the treatment of drug-resistant tuberculosis: a systematic review and meta-analysis | Zendy

Teesta Dey | Zendy; Grania Brigden | Zendy; Helen Cox | Zendy; Zara Shubber | Zendy; Graham Cooke | Zendy; Nathan Ford | Zendy

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Outcomes of clofazimine for the treatment of drug-resistant tuberculosis: a systematic review and meta-analysis

Author(s) -

Teesta Dey,

Grania Brigden,

Helen Cox,

Zara Shubber,

Graham Cooke,

Nathan Ford

Publication year - 2012

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dks389

Subject(s) - clofazimine , meta analysis , medicine , tuberculosis , drug , systematic review , medline , intensive care medicine , pharmacology , immunology , biology , leprosy , pathology , biochemistry

Current anti-tuberculosis therapeutics are not sufficiently effective against drug-resistant tuberculosis (DR-TB), and there is a need for new drugs and therapeutic approaches. It has been proposed that repurposing clofazimine for DR-TB treatment might be one way to increase therapeutic options.

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