Contribution of OqxAB efflux pumps to quinolone resistance in extended-spectrum- -lactamase-producing Klebsiella pneumoniae | Zendy

José Manuel Rodríguez-Martínez | Zendy; Paula Díaz de Alba | Zendy; A. Briales | Zendy; Jesús Machuca | Zendy; M. Lossa | Zendy; Felipe Fernández-Cuenca | Zendy; Jesús RodríguezBaño | Zendy; Luis MartínezMartínez | Zendy; Álvaro Pascual | Zendy

Open Access

Contribution of OqxAB efflux pumps to quinolone resistance in extended-spectrum- -lactamase-producing Klebsiella pneumoniae

Author(s) -

José Manuel Rodríguez-Martínez,

Paula Díaz de Alba,

A. Briales,

Jesús Machuca,

M. Lossa,

Felipe Fernández-Cuenca,

Jesús RodríguezBaño,

Luis MartínezMartínez,

Álvaro Pascual

Publication year - 2012

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dks377

Subject(s) - klebsiella pneumoniae , plasmid , microbiology and biotechnology , efflux , quinolone , biology , transformation (genetics) , gene , escherichia coli , antibiotics , genetics

The aims of this study were to analyse the presence of oqxA and oqxB genes in a collection of extended-spectrum β-lactamase (ESBL)-producing Klebsiella pneumoniae strains, to determine their chromosomal and/or plasmidic locations and to analyse expression levels in relation to susceptibility or resistance to quinolones.

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