In vivo antibiofilm effect of cerium, chitosan and hamamelitannin against usual agents of catheter-related bloodstream infections | Zendy

L. Cobrado | Zendy; Ana Silva-Dias | Zendy; Maria Manuel Azevedo | Zendy; Cidália PinaVaz | Zendy; Acácio G. Rodrigues | Zendy

Open Access

In vivo antibiofilm effect of cerium, chitosan and hamamelitannin against usual agents of catheter-related bloodstream infections

Author(s) -

L. Cobrado,

Ana Silva-Dias,

Maria Manuel Azevedo,

Cidália PinaVaz,

Acácio G. Rodrigues

Publication year - 2012

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dks376

Subject(s) - biofilm , staphylococcus epidermidis , candida albicans , microbiology and biotechnology , in vivo , acinetobacter baumannii , chitosan , chemistry , antiseptic , staphylococcus aureus , corpus albicans , biology , bacteria , pseudomonas aeruginosa , biochemistry , genetics , organic chemistry

Catheter-related bloodstream infections (CRBSIs) are common healthcare-associated infections associated with increased morbidity and medical costs. Antiseptic- and antibiotic-coated central venous catheters (CVCs) have been proposed to reduce the incidence of CRBSIs, with variable success. The aim of this study was to determine the in vivo antibiofilm activity of biocompatible and inexpensive compounds, such as cerium nitrate, chitosan and hamamelitannin, against usual agents of CRBSIs.

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