Oritavancin does not induce Clostridium difficile germination and toxin production in hamsters or a human gut model | Zendy

Jane Freeman | Zendy; Miriam Marquis | Zendy; G. S. Crowther | Zendy; S. L. Todhunter | Zendy; Warren N. Fawley | Zendy; C. H. Chilton | Zendy; Greg Moeck | Zendy; Dario Lehoux | Zendy; Mark H. Wilcox | Zendy

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Oritavancin does not induce Clostridium difficile germination and toxin production in hamsters or a human gut model

Author(s) -

Jane Freeman,

Miriam Marquis,

G. S. Crowther,

S. L. Todhunter,

Warren N. Fawley,

C. H. Chilton,

Greg Moeck,

Dario Lehoux,

Mark H. Wilcox

Publication year - 2012

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dks309

Subject(s) - clostridium difficile , microbiology and biotechnology , clindamycin , vancomycin , spore , hamster , toxin , biology , clostridium difficile toxin a , antibiotics , pharmacology , bacteria , staphylococcus aureus , endocrinology , genetics

To evaluate the relative propensities of oritavancin and vancomycin to induce Clostridium difficile infection (CDI) in hamster and in vitro human gut models.

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