Activity of delafloxacin against methicillin-resistant Staphylococcus aureus: resistance selection and characterization
Author(s) -
Jacques Rémy,
C. A. Tow-Keogh,
Timothy McConnell,
Jerrard D'Alton,
J. A. DeVito
Publication year - 2012
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dks307
Subject(s) - staphylococcus aureus , microbiology and biotechnology , methicillin resistant staphylococcus aureus , quinolone , antibiotic resistance , antibacterial agent , antibiotics , medicine , selection (genetic algorithm) , biology , bacteria , genetics , artificial intelligence , computer science
To determine the potential for delafloxacin to select for resistant mutants in methicillin-resistant Staphylococcus aureus (MRSA), including isolates with existing mutations in the quinolone resistance determining region (QRDR).
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