Effect of gastric bypass surgery on azithromycin oral bioavailability | Zendy

Raj Padwal | Zendy; Mohamed BenEltriki | Zendy; X. Wang | Zendy; L.-A. Langkaas | Zendy; Abhinav Sharma | Zendy; Daniel W. Birch | Zendy; Shahzeer Karmali | Zendy; Dion R. Brocks | Zendy

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Effect of gastric bypass surgery on azithromycin oral bioavailability

Author(s) -

Raj Padwal,

Mohamed BenEltriki,

X. Wang,

L.-A. Langkaas,

Abhinav Sharma,

Daniel W. Birch,

Shahzeer Karmali,

Dion R. Brocks

Publication year - 2012

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dks177

Subject(s) - azithromycin , medicine , pharmacokinetics , gastroenterology , bioavailability , body mass index , gastric bypass , anesthesia , surgery , pharmacology , antibiotics , obesity , weight loss , chemistry , biochemistry

Azithromycin is used widely for community-acquired infections. The timely administration of azithromycin in adequate doses minimizes treatment failure. Gastric bypass, a procedure that circumvents the upper gut, may compromise azithromycin plasma levels. We hypothesized that azithromycin concentrations would be reduced following gastric bypass.

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