Prospective multicentre feasibility study of a quality of care indicator for intravenous to oral switch therapy with highly bioavailable antibiotics | Zendy

Franky Buyle | Zendy; Sigrid Metz-Gercek | Zendy; Reli Mechtler | Zendy; Winfried V. Kern | Zendy; Hugo Robays | Zendy; Dirk Vogelaers | Zendy; Marc Struelens | Zendy

Open Access

Prospective multicentre feasibility study of a quality of care indicator for intravenous to oral switch therapy with highly bioavailable antibiotics

Author(s) -

Franky Buyle,

Sigrid Metz-Gercek,

Reli Mechtler,

Winfried V. Kern,

Hugo Robays,

Dirk Vogelaers,

Marc Struelens

Publication year - 2012

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dks145

Subject(s) - bioavailability , medicine , antibiotics , intravenous therapy , intensive care medicine , antimicrobial , intravenous antibiotics , pharmacology , chemistry , organic chemistry , microbiology and biotechnology , biology

Enhanced oral (po) bioavailability of antimicrobial drugs allows conversion to po therapy once a patient meets defined clinical criteria. This can reduce length of hospital stay, healthcare costs and risk of complications related to intravenous (iv) access. We developed a quality indicator for assessing the appropriate iv-to-po switch of bioavailable antibiotics and evaluated its feasibility and clinical relevance across acute healthcare systems.

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