Inhibitory activity of garenoxacin against DNA gyrase of Mycoplasma pneumoniae | Zendy

Maria Nakatani | Zendy; Shingo Mizunaga | Zendy; Masahiro Takahata | Zendy; Nobuhiko Nomura | Zendy

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Inhibitory activity of garenoxacin against DNA gyrase of Mycoplasma pneumoniae

Author(s) -

Maria Nakatani,

Shingo Mizunaga,

Masahiro Takahata,

Nobuhiko Nomura

Publication year - 2012

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dks140

Subject(s) - dna gyrase , dna supercoil , gatifloxacin , microbiology and biotechnology , sparfloxacin , quinolone , moxifloxacin , mycoplasma pneumoniae , chemistry , biology , escherichia coli , levofloxacin , antibiotics , dna , ofloxacin , ciprofloxacin , gene , medicine , biochemistry , dna replication , pneumonia

Garenoxacin, a des-fluoro(6)-quinolone, exhibits potent activity against Mycoplasma pneumoniae, including macrolide-resistant strains. There has been no report on the inhibitory activity of garenoxacin against the target enzyme of M. pneumoniae.

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