Standardizing an in vitro procedure for the evaluation of the antimicrobial activity of wound dressings and the assessment of three wound dressings | Zendy

О. В. Ткаченко | Zendy; J.A. Karas | Zendy

Open Access

Standardizing an in vitro procedure for the evaluation of the antimicrobial activity of wound dressings and the assessment of three wound dressings

Author(s) -

О. В. Ткаченко,

J.A. Karas

Publication year - 2012

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dks110

Subject(s) - antimicrobial , staphylococcus aureus , pseudomonas aeruginosa , microbiology and biotechnology , wound dressing , medicine , chemistry , bacteria , biology , materials science , genetics , composite material

A wide selection of wound dressings is available on the market with varying claims of antimicrobial efficacy. A valid standard method for evaluation of their antimicrobial activity in vitro has not been established. In this study we suggest a standardized time-kill assay procedure for antimicrobial activity evaluation of wound dressings in order to make studies more comparable and reproducible. We also tested two silver-containing dressings and one propolis-containing dressing against Staphylococcus aureus, Streptococcus pyogenes, Escherichia coli and Pseudomonas aeruginosa using our proposed procedure.

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