Resistant minority species are rarely observed in patients on darunavir/ritonavir monotherapy
Author(s) -
Sidonie Lambert-Niclot,
Philippe Flandre,
M. A. Valantin,
Gilles Peytavin,
Sophie Sayon,
Laurence MorandJoubert,
Constance Delaugerre,
M. Algarte-Genin,
Christine Katlama,
Vincent Cálvez,
AnneGeneviève Marcelin
Publication year - 2012
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dks052
Subject(s) - darunavir , ritonavir , virology , medicine , viral load , drug resistance , oncology , biology , virus , genetics , antiretroviral therapy
To analyse the emergence of resistant viruses in patients failing darunavir monotherapy, including minority species, and to investigate the impact of baseline reverse transcriptase (RT), protease (PR) and gag resistance mutations on virological failure (VF) occurrence.
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