Cerium, chitosan and hamamelitannin as novel biofilm inhibitors?
Author(s) -
L. Cobrado,
Maria Manuel Azevedo,
Ana Silva-Dias,
J. P. Ramos,
Cidália PinaVaz,
Acácio G. Rodrigues
Publication year - 2012
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dks007
Subject(s) - biofilm , antimicrobial , chitosan , microbiology and biotechnology , colonization , antibacterial agent , chemistry , medicine , bacteria , biology , antibiotics , biochemistry , genetics
The colonization of indwelling medical devices and subsequent biofilm formation represents a global challenge since it promotes the persistence of infection and contributes to antimicrobial resistance. The aim of this study was to determine the antimicrobial activity of cerium, chitosan and hamamelitannin against usual microbial colonizers and to assess their efficacy regarding biofilm formation on polyurethane (PUR)-like catheters.
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