Validation of novel fluorescence assays for the routine screening of drug susceptibilities of Trichomonas vaginalis
Author(s) -
Manal J. Natto,
Francesca Savioli,
Neils B. Quashie,
Christophe Dardonville,
Boris Rodenko,
Harry P. de Koning
Publication year - 2012
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkr572
Subject(s) - resazurin , trichomonas vaginalis , plate reader , high throughput screening , chemistry , viability assay , propidium iodide , metabolite , trichomoniasis , biochemistry , biology , fluorescence , microbiology and biotechnology , in vitro , programmed cell death , physics , quantum mechanics , medicine , apoptosis , pathology
To evaluate existing protocols, based on Alamar blue (resazurin), for the routine determination of drug susceptibility in trichomonads, develop new ones and validate these by screening small antiprotozoal libraries.
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