Open AccessMultiple-dose pharmacokinetics of daptomycin during continuous venovenous haemodiafiltration
Author(s) -
J. M. Wenisch,
B Meyer,
Valentin Fuhrmann,
K. Saria,
C. Zuba,
P. Dittrich,
Florian Thalhammer
Publication year - 2011
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkr551
Subject(s) - daptomycin , pharmacokinetics , medicine , dosing , trough concentration , antibacterial agent , pharmacology , antibiotics , chemistry , vancomycin , staphylococcus aureus , biology , bacteria , biochemistry , genetics
Daptomycin is bactericidal against Gram-positive bacteria, with peak-dependent effect but trough-dependent toxicity. This study was performed to develop dosing recommendations in continuous venovenous haemodialtration (CVVHDF).
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