Lopinavir/ritonavir single agent therapy as a universal combination antiretroviral therapy stopping strategy: results from the STOP 1 and STOP 2 studies
Author(s) -
Stephen Taylor,
A. Jayasuriya,
Martin Fisher,
Sris Allan,
Edmund Wilkins,
G Gilleran,
Lynn M. Heald,
Sarah Fidler,
Andrew Owen,
David Back,
Erasmus Smit
Publication year - 2011
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkr491
Subject(s) - lopinavir , lopinavir/ritonavir , antiretroviral therapy , ritonavir , medicine , cart , rescue therapy , human immunodeficiency virus (hiv) , virology , intensive care medicine , viral load , mechanical engineering , engineering
We designed two different studies to evaluate two different combination antiretroviral therapy (cART) stopping strategies namely a 'staggered stop' approach (STOP 1 study) and a 'protected stop' approach (STOP 2 study) to find the best 'universal stop' strategy.
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