Antiviral effect of raltegravir on HTLV-1 carriers
Author(s) -
Ana Treviño,
Patricia Parra,
Tamara Bar-Magen,
Carmen Garrido,
Carmen de Mendoza,
Vincent Soriano
Publication year - 2011
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkr404
Subject(s) - raltegravir , integrase inhibitor , peripheral blood mononuclear cell , virology , tropical spastic paraparesis , viral load , human t lymphotropic virus , asymptomatic , integrase , asymptomatic carrier , medicine , biology , immunology , virus , myelopathy , in vitro , human immunodeficiency virus (hiv) , antiretroviral therapy , genetics , psychiatry , spinal cord
In vitro studies support that integrase inhibitors, such as raltegravir, may inhibit human T cell lymphotropic virus type 1 (HTLV-1) replication. However, this hypothesis has not been tested in vivo.
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