Combinatorial activities of ionic silver and sodium hexametaphosphate against microorganisms associated with chronic wounds | Zendy

Gavin J. Humphreys | Zendy; Gongjun Lee | Zendy; Steven L. Percival | Zendy; Andrew J. McBain | Zendy

Open Access

Combinatorial activities of ionic silver and sodium hexametaphosphate against microorganisms associated with chronic wounds

Author(s) -

Gavin J. Humphreys,

Gongjun Lee,

Steven L. Percival,

Andrew J. McBain

Publication year - 2011

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkr350

Subject(s) - biofilm , microbiology and biotechnology , polyphosphate , antimicrobial , chemistry , staphylococcus aureus , candida albicans , sodium hexametaphosphate , bacteria , minimum inhibitory concentration , biology , sodium , biochemistry , phosphate , genetics , organic chemistry

There is growing evidence to suggest that biofilms may be involved in the aetiology of chronic wounds. The development of formulations with enhanced anti-biofilm activity could therefore represent a potential therapeutic strategy by reducing bioburdens. Here, the antimicrobial properties of ionic silver and sodium hexametaphosphate (polyphosphate) against bacteria in planktonic form and as biofilms were investigated.

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