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There is growing evidence to suggest that biofilms may be involved in the aetiology of chronic wounds. The development of formulations with enhanced anti-biofilm activity could therefore represent a potential therapeutic strategy by reducing bioburdens. Here, the antimicrobial properties of ionic silver and sodium hexametaphosphate (polyphosphate) against bacteria in planktonic form and as biofilms were investigated.

Combinatorial activities of ionic silver and sodium hexametaphosphate against microorganisms associated with chronic wounds