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Drug resistance prevalence and HIV-1 variant characterization in the naive and pretreated HIV-1-infected paediatric population in Madrid, Spain
Author(s) -
Miguel de Mulder Rougvie,
Gonzalo Yebra,
Leticia Martín,
Luis Prieto,
María José Mellado,
Pablo Rojo,
María Ángeles MuñozFernández,
Santiago Jiménez de Ory,
J. T. Ramos,
África Holguín,
M. José,
María Isabel González-Tomé,
M.D. Gurbindo,
María Luisa Navarro,
Jesús SaavedraLozano,
Rafaël Delgado,
Pablo Martín-Fontelos,
Sara Guillén,
José Simón Martínez-Castañeda,
Miguel Ángel Roa,
José Beceiro,
Adriavas,
I. Gonzalez-Granados,
Daniel BlázquezGamero
Publication year - 2011
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkr305
Subject(s) - virology , drug resistance , reverse transcriptase , hiv drug resistance , population , nucleoside reverse transcriptase inhibitor , cohort , medicine , human immunodeficiency virus (hiv) , biology , viral load , resistance mutation , antiretroviral therapy , polymerase chain reaction , genetics , gene , environmental health
Drug resistance mutations affect antiretroviral therapy (ART) effectiveness in HIV-1-infected children, compromising long-term therapy. HIV-1 variants and drug resistance mutations were identified in HIV-infected children from Madrid, Spain.

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