In vitro interaction of caspofungin and immunosuppressives against agents of mucormycosis | Zendy

Mili Thakur | Zendy; Sanjay G. Revankar | Zendy

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In vitro interaction of caspofungin and immunosuppressives against agents of mucormycosis

Author(s) -

Mili Thakur,

Sanjay G. Revankar

Publication year - 2011

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkr297

Subject(s) - caspofungin , calcineurin , sirolimus , pharmacology , microbiology and biotechnology , antagonism , biology , chemistry , antifungal , amphotericin b , medicine , transplantation , biochemistry , receptor

Mucormycosis is a rare but refractory mycosis with high mortality. Few therapeutic options are available and novel strategies are needed. Calcineurin inhibitors are known to have antifungal activity, including synergy with various antifungals. We examined the interaction of caspofungin with calcineurin inhibitors and sirolimus against Glomeromycetes.

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