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Impaired fitness of Mycobacterium tuberculosis resistant isolates in a cell culture model of murine macrophages
Author(s) -
Emma Rey-Jurado,
Griselda Tudó,
Sònia Borrell,
Fernando Alcaide,
Pere Coll,
Montserrat Español,
N Martín-Casabona,
Virginie Mick,
M. Montemayor,
Rita Moure,
M. Salvadó,
E. Vicente,
Juan Vicente GonzálezMartín
Publication year - 2011
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkr288
Subject(s) - isoniazid , mycobacterium tuberculosis , microbiology and biotechnology , biology , tuberculosis , drug resistance , multiple drug resistance , cell culture , rifampicin , virology , antibiotics , medicine , genetics , pathology
We analysed the ability of Mycobacterium tuberculosis clinical isolates to penetrate and grow inside murine macrophages as a surrogate of fitness.

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