High prevalence of extended-spectrum -lactamases and qnr determinants in Citrobacter species from Japan: dissemination of CTX-M-2 | Zendy

Hajime Kanamori | Zendy; Hisakazu Yano | Zendy; Yoichi Hirakata | Zendy; Shiro Endo | Zendy; Kenichi Arai | Zendy; Miho Ogawa | Zendy; Mie Shimojima | Zendy; Tetsuji Aoyagi | Zendy; Mochammad Hatta | Zendy; Mitsuhiro Yamada | Zendy; Katsushi Nishimaki | Zendy; Miho Kitagawa | Zendy; Hiroyuki Kunishima | Zendy; Mitsuo Kaku | Zendy

Open Access

High prevalence of extended-spectrum -lactamases and qnr determinants in Citrobacter species from Japan: dissemination of CTX-M-2

Author(s) -

Hajime Kanamori,

Hisakazu Yano,

Yoichi Hirakata,

Shiro Endo,

Kenichi Arai,

Miho Ogawa,

Mie Shimojima,

Tetsuji Aoyagi,

Mochammad Hatta,

Mitsuhiro Yamada,

Katsushi Nishimaki,

Miho Kitagawa,

Hiroyuki Kunishima,

Mitsuo Kaku

Publication year - 2011

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkr283

Subject(s) - citrobacter , enterobacteriaceae , microbiology and biotechnology , plasmid , biology , concomitant , quinolone , antibiotics , medicine , escherichia coli , genetics , gene

Extended-spectrum β-lactamases (ESBLs) have become a problem among AmpC-producing Enterobacteriaceae and the emergence of concomitant quinolone resistance in β-lactamase-producing isolates poses a global threat. In this study we investigated the prevalence and regional variation of ESBLs in Japanese clinical isolates of Citrobacter spp. and analysed plasmid-mediated quinolone resistance (PMQR) determinants in ESBL-producing Citrobacter spp.

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