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Changing epidemiology of central venous catheter-related bloodstream infections: increasing prevalence of Gram-negative pathogens
Author(s) -
Miguel Marcos,
Álex Soriano,
Amaia Iñurrieta,
J. A. Martínez,
Adalgiza Reyes Romero,
N. Cobos,
Cristina Hernández,
Manuel Almela,
Francesc Marco,
Josep Mensa
Publication year - 2011
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkr231
Subject(s) - medicine , central venous catheter , epidemiology , incidence (geometry) , gram , catheter , surgery , biology , optics , genetics , physics , bacteria
Gram-positive microorganisms have been the predominant pathogens in central venous catheter-related bloodstream infections (CRBSIs). Recent guidelines recommend empirical therapy according to this and restrict coverage for Gram-negatives to specific circumstances. This study aimed to analyse the epidemiological changes in CRBSIs over the 1991-2008 period and to analyse predictors of Gram-negative CRBSIs.

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