Multidrug-resistant tuberculosis (MDR-TB) treatment in the UK: a study of injectable use and toxicity in practice
Author(s) -
Ann Sturdy,
Anna L. Goodman,
Ricardo J. José,
Angela Loyse,
M. O'Donoghue,
Onn Min Kon,
Martin Dedicoat,
Thomas S. Harrison,
Laurence John,
Marc Lipman,
Graham Cooke
Publication year - 2011
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkr221
Subject(s) - ototoxicity , capreomycin , medicine , amikacin , tuberculosis , intensive care medicine , pediatrics , surgery , antibiotics , mycobacterium tuberculosis , chemotherapy , ethambutol , pathology , microbiology and biotechnology , cisplatin , biology
Multidrug-resistant tuberculosis (MDR-TB) is an increasing challenge to health services globally. Although new drugs are in development, current guidelines still recommend prolonged use of injectable antimicrobials (usually amikacin, kanamycin or capreomycin). The evidence base to inform treatment and monitoring strategies is very limited.
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