Optimizing ciprofloxacin dosing in intensive care unit patients through the use of population pharmacokinetic-pharmacodynamic analysis and Monte Carlo simulations | Zendy

Dalia Khachman | Zendy; JeanMarie Conil | Zendy; B. Georges | Zendy; Sylvie Saivin | Zendy; Georges Houin | Zendy; PierreLouis Toutain | Zendy; Céline M. Laffont | Zendy

Open Access

Optimizing ciprofloxacin dosing in intensive care unit patients through the use of population pharmacokinetic-pharmacodynamic analysis and Monte Carlo simulations

Author(s) -

Dalia Khachman,

JeanMarie Conil,

B. Georges,

Sylvie Saivin,

Georges Houin,

PierreLouis Toutain,

Céline M. Laffont

Publication year - 2011

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkr220

Subject(s) - dosing , intensive care unit , pharmacodynamics , medicine , pharmacokinetics , ciprofloxacin , intensive care , intensive care medicine , population , pharmacology , antibiotics , biology , microbiology and biotechnology , environmental health

To explore different ciprofloxacin dosage regimens for the treatment of intensive care unit (ICU) patients with respect to clinical outcome and the development of bacterial resistance for the major Gram-negative pathogens.

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