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Molecular analysis of ciprofloxacin resistance and clonal relatedness of clinical Escherichia coli isolates from haematology patients receiving ciprofloxacin prophylaxis
Author(s) -
B.C. van Hees,
M. Tersmette,
Rob J. L. Willems,
Bouke C. de Jong,
Douwe H. Biesma,
Erik J. van Hannen
Publication year - 2011
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkr216
Subject(s) - ciprofloxacin , microbiology and biotechnology , biology , escherichia coli , hematology , dna gyrase , drug resistance , antibiotics , antibiotic resistance , antibacterial agent , genetics , immunology , gene
Widespread use of fluoroquinolones has led to increased levels of resistance in clinical isolates of Escherichia coli. We investigated the evolution of ciprofloxacin susceptibility and molecular epidemiology of clinical E. coli isolates in haematology patients receiving ciprofloxacin prophylaxis on the population and individual patient level.

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