Serial measurement of the C-reactive protein is a poor predictor of treatment outcome in prosthetic joint infection
Author(s) -
Philip Bejon,
Ivor Byren,
Bridget L. Atkins,
Matthew Scarborough,
Andrew Woodhouse,
P. McLardy-Smith,
Roger Gundle,
Anthony R. Berendt
Publication year - 2011
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkr182
Subject(s) - c reactive protein , medicine , outcome (game theory) , surgery , inflammation , mathematics , mathematical economics
Prosthetic joint infection is usually treated using surgery and antibiotics. The response to the treatment regimen is often evaluated using serial monitoring of plasma C-reactive protein (CRP) concentrations. In order to examine how useful this monitoring is, we calculated the sensitivity and specificity of CRP concentrations for predicting treatment failure.
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