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Identification of antimicrobial activity among FDA-approved drugs for combating Mycobacterium abscessus and Mycobacterium chelonae
Author(s) -
Sidharth Chopra,
Kiminori Matsuyama,
Christina L. Hutson,
Peter B. Madrid
Publication year - 2011
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkr154
Subject(s) - mycobacterium chelonae , mycobacterium abscessus , antimicrobial , microbiology and biotechnology , mycobacterium , medicine , identification (biology) , biology , tuberculosis , pathology , botany
Rapidly growing mycobacteria have long been neglected in drug discovery efforts and this neglect is reflected in the paucity of therapeutic options available for diseases resulting from these infections. The purpose of this work is to identify new candidate drugs for treating non-tuberculous mycobacteria (NTM) by testing FDA-approved drugs for antimicrobial activity against Mycobacterium abscessus and Mycobacterium chelonae, two emerging NTM drug-resistant pathogens.

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