Inhibition of hepatitis C virus replication by semi-synthetic derivatives of glycopeptide antibiotics | Zendy

Susan Obeid | Zendy; S. S. Printsevskaya | Zendy; Eugenia N. Olsufyeva | Zendy; Kai Dallmeier | Zendy; David Durantel | Zendy; Fabien Zoulim | Zendy; M. N. Preobrazhenskaya | Zendy; Johan Neyts | Zendy; Jan Paeshuyse | Zendy

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Inhibition of hepatitis C virus replication by semi-synthetic derivatives of glycopeptide antibiotics

Author(s) -

Susan Obeid,

S. S. Printsevskaya,

Eugenia N. Olsufyeva,

Kai Dallmeier,

David Durantel,

Fabien Zoulim,

M. N. Preobrazhenskaya,

Johan Neyts,

Jan Paeshuyse

Publication year - 2011

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkr104

Subject(s) - replicon , hepatitis c virus , biology , virology , teicoplanin , protease inhibitor (pharmacology) , ns2 3 protease , protease , virus , microbiology and biotechnology , biochemistry , viral load , enzyme , vancomycin , plasmid , genetics , bacteria , dna , antiretroviral therapy , staphylococcus aureus

Some semi-synthetic derivatives of glycopeptide antibiotics have been shown to exert in vitro antiviral activity against HIV and coronaviruses. Here we report and characterize the in vitro anti-hepatitis C virus (HCV) activity of several semi-synthetic derivatives of teicoplanin aglycone.

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