Radical reduction of cephalosporin use at a tertiary hospital after educational antibiotic intervention during an outbreak of extended-spectrum β-lactamase-producing Klebsiella pneumoniae
Author(s) -
Thomas Tängdén,
BrittMarie Eriksson,
Åsa Melhus,
Bodil Svennblad,
Otto Cars
Publication year - 2011
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkr053
Subject(s) - cephalosporin , medicine , klebsiella pneumoniae , tazobactam , piperacillin , antibiotics , antibiotic resistance , carbapenem , outbreak , piperacillin/tazobactam , pseudomonas aeruginosa , microbiology and biotechnology , intensive care medicine , escherichia coli , biology , imipenem , virology , bacteria , genetics , gene , biochemistry
During an outbreak of extended-spectrum β-lactamase (ESBL)-producing Klebsiella pneumoniae at our hospital, we performed an educational antibiotic intervention aimed at reducing prescriptions of second- and third-generation cephalosporins and preventing increased use of fluoroquinolones and carbapenems. In this report, we describe the implementation strategy used and evaluate the intervention effect according to Cochrane recommendations.
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