In vitro interactions between sitamaquine and amphotericin B, sodium stibogluconate, miltefosine, paromomycin and pentamidine against Leishmania donovani | Zendy

Karin Seifert | Zendy; Jane C. Munday | Zendy; Tauqeerunnisa Syeda | Zendy; Simon L. Croft | Zendy

Open Access

In vitro interactions between sitamaquine and amphotericin B, sodium stibogluconate, miltefosine, paromomycin and pentamidine against Leishmania donovani

Author(s) -

Karin Seifert,

Jane C. Munday,

Tauqeerunnisa Syeda,

Simon L. Croft

Publication year - 2011

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkq542

Subject(s) - miltefosine , sodium stibogluconate , paromomycin , pentamidine , leishmania donovani , amastigote , pharmacology , amphotericin b , leishmania , microbiology and biotechnology , biology , leishmaniasis , medicine , immunology , antibiotics , cutaneous leishmaniasis , visceral leishmaniasis , parasite hosting , aminoglycoside , antifungal , world wide web , computer science , pneumonia

To evaluate in vitro interactions between sitamaquine and the current antileishmanial drugs amphotericin B, sodium stibogluconate, miltefosine, paromomycin and pentamidine against intracellular Leishmania donovani amastigotes in peritoneal mouse macrophages. A second objective was to evaluate the susceptibility of antimony-resistant L. donovani isolates to sitamaquine.

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