Emergence of fluoroquinolone-resistant Streptococcus pyogenes in Japan by a point mutation leading to a new amino acid substitution | Zendy

K.I. Arai | Zendy; Yoichi Hirakata | Zendy; Hisakazu Yano | Zendy; Hajime Kanamori | Zendy; S. Endo | Zendy; Atsushi Hirotani | Zendy; Yuko Abe | Zendy; Maho Nagasawa | Zendy; Miho Kitagawa | Zendy; Tetsuji Aoyagi | Zendy; M. Hatta | Zendy; Mitsuhiro Yamada | Zendy; Katsushi Nishimaki | Zendy; Yoshinaga Takayama | Zendy; Naoki Yamamoto | Zendy; Hiroyuki Kunishima | Zendy; Mitsuo Kaku | Zendy

Open Access

Emergence of fluoroquinolone-resistant Streptococcus pyogenes in Japan by a point mutation leading to a new amino acid substitution

Author(s) -

K.I. Arai,

Yoichi Hirakata,

Hisakazu Yano,

Hajime Kanamori,

S. Endo,

Atsushi Hirotani,

Yuko Abe,

Maho Nagasawa,

Miho Kitagawa,

Tetsuji Aoyagi,

M. Hatta,

Mitsuhiro Yamada,

Katsushi Nishimaki,

Yoshinaga Takayama,

Naoki Yamamoto,

Hiroyuki Kunishima,

Mitsuo Kaku

Publication year - 2010

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkq477

Subject(s) - streptococcus pyogenes , point mutation , cytosine , levofloxacin , microbiology and biotechnology , genotype , biology , quinolone , mutation , gene , genetics , antibiotics , staphylococcus aureus , bacteria

Streptococcus pyogenes causes various diseases in humans. While the prevalence of fluoroquinolone-resistant S. pyogenes isolates has been increasing since 2000 in the USA and Europe, it has remained very low in Japan. We isolated a fluoroquinolone-resistant S. pyogenes strain and analysed its genetics.

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