Antimicrobial activity of a novel aminoglycoside, ACHN-490, against Acinetobacter baumannii and Pseudomonas aeruginosa from New York City | Zendy

David Landman | Zendy; Paul Kelly | Zendy; Martín Bäcker | Zendy; Ellappan Babu | Zendy; Neil V. Shah | Zendy; Simona Bratu | Zendy; John Quale | Zendy

Open Access

Antimicrobial activity of a novel aminoglycoside, ACHN-490, against Acinetobacter baumannii and Pseudomonas aeruginosa from New York City

Author(s) -

David Landman,

Paul Kelly,

Martín Bäcker,

Ellappan Babu,

Neil V. Shah,

Simona Bratu,

John Quale

Publication year - 2010

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkq459

Subject(s) - acinetobacter baumannii , pseudomonas aeruginosa , aminoglycoside , microbiology and biotechnology , antimicrobial , polymyxin , acinetobacter , biology , antibiotics , bacteria , genetics

Multidrug-resistant Acinetobacter baumannii and Pseudomonas aeruginosa have become a global problem, often leaving the polymyxins as therapeutic agents of last resort. ACHN-490, a next-generation aminoglycoside with activity against a broad range of Gram-positive and Gram-negative pathogens, was examined against clinical isolates of A. baumannii and P. aeruginosa.

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