Open AccessThe role of Escherichia coli YrbB in the lethal action of quinolones
Author(s) -
Ximeng Han,
Peng Geng,
Lijun Zhang,
Tao Lu
Publication year - 2010
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkq427
Subject(s) - nalidixic acid , escherichia coli , sos response , microbiology and biotechnology , mechanism of action , antimicrobial , quinolone , antitoxin , biology , chemistry , hydroxyl radical , antibiotics , toxin , biochemistry , ciprofloxacin , radical , gene , in vitro
To explore bacterial cellular factors that protect against the lethal effect of antimicrobial stress as potential targets of antimicrobial potentiators, the role of Escherichia coli YrbB in protecting cells from quinolone-mediated cell death was studied.
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