Treatment of progressive multifocal leukoencephalopathy and idiopathic CD4+ lymphocytopenia | Zendy

Amila Patel | Zendy; J. Patel | Zendy; Judy O. Ikwuagwu | Zendy

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Treatment of progressive multifocal leukoencephalopathy and idiopathic CD4+ lymphocytopenia

Author(s) -

Amila Patel,

J. Patel,

Judy O. Ikwuagwu

Publication year - 2010

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkq389

Subject(s) - lymphocytopenia , progressive multifocal leukoencephalopathy , medicine , jc virus , leukoencephalopathy , pediatrics , disease , pathology , virus , immunology , lymphocyte

Progressive multifocal leukoencephalopathy is a neurological disease caused by the human polyoma virus JC virus and can present in patients with known immunodeficiencies. However, when associated with idiopathic CD4+ lymphocytopenia, management of patients can be quite challenging as these are two rare diseases with limited effective treatment options. In conjunction with the case report of a patient diagnosed with both conditions presented within this issue, a discussion of available treatment strategies is detailed.

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