Open AccessTribal ethnicity and CYP2B6 genetics in Ugandan and Zimbabwean populations in the UK: implications for efavirenz dosing in HIV infection
Author(s) -
Yalda Jamshidi,
Michelle Moreton,
Denise A. McKeown,
Susan Andrews,
T. Nithiyananthan,
Lorna Tinworth,
David W. Holt,
S Tariq Sadiq
Publication year - 2010
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkq369
Subject(s) - efavirenz , haplotype , genotype , single nucleotide polymorphism , genetics , biology , allele , gene , antiretroviral therapy , viral load , virus
To determine differences in CYP2B6 loss of function (LoF) single nucleotide polymorphisms (SNPs) and haplotypes between Zimbabweans and Ugandans, and within Ugandan populations (Bantu and Nilotic).
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