Drug-resistant cytomegalovirus in transplant recipients: a French cohort study | Zendy

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Drug-resistant cytomegalovirus in transplant recipients: a French cohort study

Author(s) -

Sébastien Hantz,

F. Garnier-Geoffroy,

MarieChristine Mazeron,

I. Garrigue,

Pierre Merville,

Catherine Mengelle,

L. Rostaing,

F. Saint Marcoux,

Marie Essig,

Jean-Philippe Rérolle,

Sébastien Cotin,

Raphaële Germi,

S. Pillet,

Y Lebranchu,

Pascal Turlure,

Sophie Alain,

G. Herbein,

A. Coaquette,

MarieEdith Lafon,

Christine Archimbaud,

C. Henquell,

H. PeigueLafeuille,

Pierre Pothier,

JeanBaptiste Bour,

Raymond Césaire,

F. Majioullah,

Patrice Morand,

Christine Morel-Baccard,

Anne Signori-Schmück,

Joël Grosjean,

Florence MorfinSherpa,

Geneviève Billaud,

Vinca Domenach,

Patrice André,

Marie-Paule Milon,

Michel Segondy,

Vincent Foulongne,

G. Agius,

A. BebyDefaux,

Bruno Pozzetto,

JeanMichel Mansuy,

S. Gaudio-Castelain,

Alexandra Ducancelle,

F. Lunel,

C. Payan,

S. Gouarin,

A. Dewilde,

Celine Bressolette,

Marianne CosteBurel,

BertheMarie ImbertMarcille,

L. Andreoletti,

Nicolas Lévêque,

Véronique Venard,

Hélène Jeulin,

S. Minjolle,

Marie Gueudin,

R. Colimon,

Françoise StollKeller,

Samira FafiKremer,

Frédéric Dubois,

Catherine Gaudy,

Paul Dény,

F. B. Vezinet,

Nadhira Houhou,

P. Honderlick,

M. LeruezVille,

P. Vaghefi,

Élisabeth Dussaix,

Henri Agut,

David Boutolleau,

Claire Deback,

Catherine Scieux,

Jérôme Le Goff,

Didier Ducloux,

Claire Vanlemmens,

Fabrice Larosa,

Martine NeauCransac,

Claire Dromer,

E. Rosier,

M Douillet,

D. Morel,

Karine Moreau,

Séverine Martin,

MarcAlain Billes,

Nöel Milpied,

R. Tabrizi,

S. Vigouroux,

Christian Mélot,

P. Deteix,

A.E. Heng,

Léandre Mackaya,

S. Casanova,

J.-O. Bay,

F Deméocq,

Frédéric Duee,

C. Mousson,

Patrick Hillon,

Alessandra Minello,

P. Charve,

Y. Tanter,

F. Bayle,

Bénédicte Janbon,

E. Borrel,

A. Boignard,

L. Neron,

C. Pison,

C. Saint-Raymond,

JeanPierre Brion,

J. Y. Cahn,

Dominique Bordessoule,

François Bompart,

Celine Philippon,

JeanClaude Aldigier,

Jean Philippe Rerolle,

Z. Dickson,

V. Leprivey,

F. Roger-Rolle,

Christophe Piguet,

Pierre Marquet,

Bruno François,

Claire PouteilNoble,

Valérie Mialou,

G. Mourad,

Christophe Mariat,

Jérôme Cornillon,

E. Tavernie-Tardy,

Michel Attal,

A. Huynh,

Lionel Rostaing,

Nassim Kamar,

D. Mencia,

Lionel Crognier,

B. H. de Ligny,

Marc Hazzan,

Pierre Bordigoni,

S. Pall-Kondolff,

Alexandra Salmon,

Lionel Clément,

Patrice Chevallier,

Steven Le Gouill,

Thomas Gastinne,

JeanJacques Delaunay,

Sameh Ayari,

T. Guillaume,

Mohamad Mohty,

Philippe Moreau,

Marie Robin,

Claire Le Houérou,

Magali Giral,

Emmanuelle Papuchon,

S. Pattier,

M. Treilhaud,

Claire Camus,

Isabelle Étienne,

Bruno Moulin,

S. Caillard-Ohlmann,

B. Lioure,

Nadine Cojean,

Philipp Lutz,

F. Uettwiller,

Natacha EntzWerlé,

A. Laplace,

Markus W. Büchler,

Christelle Barbet,

Dominique Fourchy,

M. Stern,

Dominique Grenet,

Michel Delahousse,

Alexandre Karras,

Faouzi Saliba,

Philippe Ichaı̈,

Nathalie Dhédin,

J P Vernant,

M. Uzunov,

Benoı̂t Barrou,

Denis Glotz,

M.-N. Péraldi,

N Langner,

Patricia Ribaud

Publication year - 2010

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkq368

Subject(s) - valganciclovir , medicine , drug resistance , ganciclovir , cohort , cytomegalovirus , foscarnet , cohort study , human cytomegalovirus , resistance mutation , prospective cohort study , virology , immunology , viral disease , virus , biology , herpesviridae , polymerase chain reaction , gene , reverse transcriptase , microbiology and biotechnology , biochemistry

Cytomegalovirus (CMV) drug resistance is a therapeutic challenge in the transplant setting. No longitudinal cohort studies of CMV resistance in a real-life setting have been published in the valganciclovir era. We report findings for a French multicentre prospective cohort of 346 patients enrolled at initial diagnosis of CMV infection (clinical trial registered at clinicaltrials.gov: NCT01008540).

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