Biodistribution and tissue toxicity of amphotericin B in mice following multiple dose administration of a novel oral lipid-based formulation (iCo-009) | Zendy

Pavel Gershkovich | Zendy; Olena Sivak | Zendy; E. K. Wasan | Zendy; Alex B. Magil | Zendy; David Owen | Zendy; J. G. Clement | Zendy; K. M. Wasan | Zendy

Open Access

Biodistribution and tissue toxicity of amphotericin B in mice following multiple dose administration of a novel oral lipid-based formulation (iCo-009)

Author(s) -

Pavel Gershkovich,

Olena Sivak,

E. K. Wasan,

Alex B. Magil,

David Owen,

J. G. Clement,

K. M. Wasan

Publication year - 2010

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkq358

Subject(s) - toxicity , pharmacology , biodistribution , kidney , oral administration , pharmacokinetics , creatinine , amphotericin b , toxicokinetics , spleen , medicine , biology , in vivo , antifungal , microbiology and biotechnology , dermatology

The purpose of this study was to assess the biodistribution and toxicity of amphotericin B (AMB) following multiple dose administration of an oral lipid-based formulation (iCo-009).

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