Impact of different empirical antibiotic treatment regimens for community-acquired pneumonia on the emergence of Clostridium difficile | Zendy

Anke H. W. Bruns | Zendy; Jan Jelrik Oosterheert | Zendy; Ed J. Kuijper | Zendy; JW Lammers | Zendy; Steven Thijsen | Zendy; Annet Troelstra | Zendy; Andy I. M. Hoepelman | Zendy

Open Access

Impact of different empirical antibiotic treatment regimens for community-acquired pneumonia on the emergence of Clostridium difficile

Author(s) -

Anke H. W. Bruns,

Jan Jelrik Oosterheert,

Ed J. Kuijper,

JW Lammers,

Steven Thijsen,

Annet Troelstra,

Andy I. M. Hoepelman

Publication year - 2010

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkq329

Subject(s) - clostridium difficile , carriage , medicine , moxifloxacin , antibiotics , community acquired pneumonia , pneumonia , odds ratio , diarrhea , microbiology and biotechnology , biology , pathology

Treatment of community-acquired pneumonia (CAP) with newer fluoroquinolones may contribute to selection for Clostridium difficile. We studied the prevalence of C. difficile carriage and C. difficile infection (CDI) on admission, and nosocomial acquisition rates in patients hospitalized for CAP and compared different empirical treatment strategies.

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