ASP2151, a novel helicase-primase inhibitor, possesses antiviral activity against varicella-zoster virus and herpes simplex virus types 1 and 2
Author(s) -
Koji Chono,
Kiyomitsu Katsumata,
Toru Kontani,
M. Kobayashi,
Keiichi Sudo,
Tomoyuki Yokota,
Katsuhiro Konno,
Yusuke Shimizu,
Hiroshi Suzuki
Publication year - 2010
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkq198
Subject(s) - primase , varicella zoster virus , virology , helicase , herpes simplex virus , biology , herpesviridae , virus , microbiology and biotechnology , biochemistry , viral disease , polymerase chain reaction , reverse transcriptase , rna , gene
To evaluate and describe the anti-herpesvirus effect of ASP2151, amenamevir, a novel non-nucleoside oxadiazolylphenyl-containing herpesvirus helicase-primase complex inhibitor.
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