Dynamics of HIV tropism under suppressive antiretroviral therapy: implications for tropism testing in subjects with undetectable viraemia | Zendy

Eduardo Seclén | Zendy; María del Mar González | Zendy; Carmen de Mendoza | Zendy; Vincent Soriano | Zendy; Eva Poveda | Zendy

Open Access

Dynamics of HIV tropism under suppressive antiretroviral therapy: implications for tropism testing in subjects with undetectable viraemia

Author(s) -

Eduardo Seclén,

María del Mar González,

Carmen de Mendoza,

Vincent Soriano,

Eva Poveda

Publication year - 2010

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkq156

Subject(s) - maraviroc , tropism , tissue tropism , context (archaeology) , virology , antiretroviral therapy , medicine , immunology , ccr5 receptor antagonist , viral load , human immunodeficiency virus (hiv) , biology , virus , chemokine , immune system , chemokine receptor , paleontology

The use of maraviroc as part of a simplification of antiretroviral therapy (ART) is hampered by the difficulty of assessing viral tropism in patients with undetectable viraemia. In this context, information on tropism might be obtained from testing either older stored viraemic sera collected before initiation of ART or current proviral DNA in peripheral blood cells.

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