Open AccessEvaluating the stability of colistin and colistin methanesulphonate in human plasma under different conditions of storage
Author(s) -
Rajesh V. Dudhani,
Roger L. Nation,
Jian Li
Publication year - 2010
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkq134
Subject(s) - colistin , pharmacokinetics , chemistry , chromatography , plasma concentration , human plasma , high performance liquid chromatography , pharmacology , medicine , antibiotics , biochemistry
The purpose of this study was to assess the stability of colistin and colistin methanesulphonate (CMS) in human plasma under storage conditions typically used in clinical pharmacokinetic (PK) and PK/pharmacodynamic (PD) investigations.
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