Open AccessQuorum-sensing regulator sdiA and marA overexpression is involved in in vitro-selected multidrug resistance of Escherichia coli
Author(s) -
María M. Tavío,
Virginia Aquili,
José B. Poveda,
Nuno T. Antunes,
Javier SánchezCéspedes,
Jordi Vilà
Publication year - 2010
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkq112
Subject(s) - ceftazidime , microbiology and biotechnology , biology , aztreonam , mutant , gene , antibiotics , genetics , imipenem , antibiotic resistance , bacteria , pseudomonas aeruginosa
The role of sdiA in the acquisition of low-level multidrug resistance (MDR) was analysed and compared with that of marA and soxS in two Escherichia coli clinical isolates and two in vitro-selected mutants.
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