Antibiotic use and impact on outcome from bacteraemic critical illness: the BActeraemia Study in Intensive Care (BASIC) | Zendy

Alberto Corona | Zendy; Guido Bertolini | Zendy; Jeffrey Lipman | Zendy; A.P.R. Wilson | Zendy; Mervyn Singer | Zendy

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Antibiotic use and impact on outcome from bacteraemic critical illness: the BActeraemia Study in Intensive Care (BASIC)

Author(s) -

Alberto Corona,

Guido Bertolini,

Jeffrey Lipman,

A.P.R. Wilson,

Mervyn Singer

Publication year - 2010

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkq088

Subject(s) - medicine , antibiotics , odds ratio , intensive care medicine , observational study , prospective cohort study , intensive care , bacteremia , epidemiology , confidence interval , biology , microbiology and biotechnology

The lack of prospective, randomized, controlled trial data to guide optimal antibiotic use in bacteraemic critically ill patients has led to a wide variety of strategies and major issues with drug resistance. We therefore prospectively investigated the epidemiology of bacteraemia and fungaemia in intensive care units (ICUs); and the impact of timing, type and appropriateness of antibiotic intervention.

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