Acidified nitrite enhances hydrogen peroxide disinfection of Acanthamoeba, bacteria and fungi | Zendy

Wayne Heaselgrave | Zendy; Peter W. Andrew | Zendy; Simon Kilvington | Zendy

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Acidified nitrite enhances hydrogen peroxide disinfection of Acanthamoeba, bacteria and fungi

Author(s) -

Wayne Heaselgrave,

Peter W. Andrew,

Simon Kilvington

Publication year - 2010

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkq075

Subject(s) - microbiology and biotechnology , antimicrobial , hydrogen peroxide , fusarium solani , biology , bacteria , serratia marcescens , candida albicans , chemistry , bacillus subtilis , biochemistry , escherichia coli , genetics , gene

In the human innate immune system, stimulated phagocytes release reactive nitrogen intermediates that can react with superoxide to form the powerful oxidant peroxynitrite and other less abundant species. In this study, the efficacy of hydrogen peroxide (H2O2) and acidified nitrite (NaNO2) alone and in combination was compared against a variety of bacteria, fungi and protozoa.

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