Open AccessCryptdin-2: a novel therapeutic agent for experimental Salmonella Typhimurium infection
Author(s) -
Simran Preet,
Indu Verma,
Praveen Rishi
Publication year - 2010
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkq066
Subject(s) - salmonella , salmonella enterica , microbiology and biotechnology , ex vivo , in vivo , antibiotics , biology , bacteria , virology , genetics
Salmonella infections represent a major health hazard and have been responsible for a number of epidemics. In view of the emergence of multidrug-resistant Salmonella strains, there is a need for therapeutic alternatives. The purpose of this study was to evaluate the therapeutic potential of cryptdin-2 (a Paneth cell antimicrobial peptide) against Salmonella infection.
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