Dissemination of two international linezolid-resistant Staphylococcus epidermidis clones in Greek hospitals | Zendy

Apostolos Liakopoulos | Zendy; Iris Spiliopoulou | Zendy; A. Damani | Zendy; Maria Kanellopoulou | Zendy; S. Schoina | Zendy; E. Papafragas | Zendy; Markos Marangos | Zendy; Fotini Fligou | Zendy; Εpameidas Zakynthinos | Zendy; Demosthènes Makris | Zendy; Efthymia Protonotariou | Zendy; F. Tsiapara | Zendy; Kriton S. Filos | Zendy; E. Diza | Zendy; Evangelos D. Anastassiou | Zendy; Efthymia Petinaki | Zendy

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Dissemination of two international linezolid-resistant Staphylococcus epidermidis clones in Greek hospitals

Author(s) -

Apostolos Liakopoulos,

Iris Spiliopoulou,

A. Damani,

Maria Kanellopoulou,

S. Schoina,

E. Papafragas,

Markos Marangos,

Fotini Fligou,

Εpameidas Zakynthinos,

Demosthènes Makris,

Efthymia Protonotariou,

F. Tsiapara,

Kriton S. Filos,

E. Diza,

Evangelos D. Anastassiou,

Efthymia Petinaki

Publication year - 2010

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkq065

Subject(s) - linezolid , multilocus sequence typing , 23s ribosomal rna , staphylococcus epidermidis , microbiology and biotechnology , multiple drug resistance , staphylococcus aureus , micrococcaceae , typing , biology , drug resistance , antibiotics , antibacterial agent , genetics , bacteria , genotype , gene , vancomycin , rna , ribosome

mutations, multilocus sequence typing, Greece,staphylococciSir,The growing number of infections caused by multidrug-resistantStaphylococcus epidermidis has necessitated the use of newantimicrobials, such as linezolid, and enhanced the emergenceof linezolid-resistant S. epidermidis strains. To date, mutations ofregion V of 23S rRNA (G2447T, T2504A, C2534T, G2576T,G2603T and G2631T) have been associated with the expressionof linezolid resistance among clinical staphylococcal isolates.

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