Novel mixed-format real-time PCR assay to detect mutations conferring resistance to triazoles in Aspergillus fumigatus and prevalence of multi-triazole resistance among clinical isolates in the Netherlands | Zendy

Corné H. W. Klaassen | Zendy; Hanneke A. de Valk | Zendy; Ilse Curfs-Breuker | Zendy; Jacques F. Meis | Zendy

Open Access

Novel mixed-format real-time PCR assay to detect mutations conferring resistance to triazoles in Aspergillus fumigatus and prevalence of multi-triazole resistance among clinical isolates in the Netherlands

Author(s) -

Corné H. W. Klaassen,

Hanneke A. de Valk,

Ilse Curfs-Breuker,

Jacques F. Meis

Publication year - 2010

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkq041

Subject(s) - aspergillus fumigatus , microbiology and biotechnology , aspergillus , biology , drug resistance , polymerase chain reaction , fungi imperfecti , triazole , genetics , gene , chemistry , organic chemistry

The aim of this study was: (i) to study the prevalence of triazole-resistant Aspergillus fumigatus isolates in the Netherlands; and (ii) to design rapid real-time PCR methods to identify such isolates.

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