Visceral leishmaniasis affects liver and spleen concentrations of amphotericin B following administration to mice | Zendy

Pavel Gershkovich | Zendy; Ellen K. Wasan | Zendy; Olena Sivak | Zendy; R. Li | Zendy; Xiaotong Zhu | Zendy; Karl A. Werbovetz | Zendy; Richard R. Tidwell | Zendy; John G. Clement | Zendy; Sheila J. Thornton | Zendy; Kishor M. Wasan | Zendy

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Visceral leishmaniasis affects liver and spleen concentrations of amphotericin B following administration to mice

Author(s) -

Pavel Gershkovich,

Ellen K. Wasan,

Olena Sivak,

R. Li,

Xiaotong Zhu,

Karl A. Werbovetz,

Richard R. Tidwell,

John G. Clement,

Sheila J. Thornton,

Kishor M. Wasan

Publication year - 2009

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkp465

Subject(s) - visceral leishmaniasis , amphotericin b , spleen , medicine , oral administration , leishmaniasis , pharmacology , ratón , immunology , antifungal , dermatology

To assess the impact of visceral leishmaniasis (VL) on the concentration of amphotericin B (AmB) recovered in the liver and spleen following either intravenous (AmBisome) or oral (iCo-009) AmB administration to mice.

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